Hi Alex. Thanks for your response. I'm using Windows 10 (64 bit). My system is very stable and nothing has changed. I have tried at least 1/2 dozen cables, all of which I have used with the AudioMoth in the past. I've been using AudioMoths for at least 4 years now and, although I know from experience that they can be a little unpredictable at times, to have all three fail to register with the configuration software, suddenly out of the blue, seems very odd as nothing on my PC setup has changed.